A Case of Thyroid Hormone Resistance
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A Case of Thyroid Hormone Resistance

J Clin Res Pediatr Endocrinol 2015;7(2):75-75
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Abstract

Thyroid hormone resistance is a hereditary disease characterized by high triiodothyronine, thyroxine, and non-suppressed thyroid-stimulating hormone. It usually shows an autosomal dominant inheritance feature. The most common is due to mutations in the thyroid hormone receptor beta (THRB) gene. Patients with thyroid hormone resistance are generally clinically euthyroid. However, although rare, signs and symptoms of hypothyroidism or thyrotoxicosis may be present. In this report, we discuss a case of thyroid hormone resistance and tachycardia; the patient had positive family history, normal intelligence level, and no goiter.

Keywords: Thyroid hormone resistance, family survey